ГЕНЕТИЧЕСКИЕ ОСНОВЫ ОСТЕОПОРОЗА
https://doi.org/10.25557/2073-7998.2018.07.3-10
Аннотация
Остеопороз (ОП) является одним из наиболее распространенных метаболических заболеваний скелета и одной из ведущих причин инвалидности и сокращения продолжительности жизни людей пожилого возраста, что делает его одной из важнейших проблем здравоохранения во всем мире. ОП — многофакторное заболевание, в развитии которого играют роль как генетические, так и средовые факторы риска. В настоящее время наблюдается значительный прогресс в изучении молекулярного патогенеза заболевания, однако исследования генетических основ ОП далеки от завершения. Знание эпидемиологии и понимание патогенеза ОП необходимы для разработки эффективных методов пресимптоматической диагностики, лечения и профилактики заболевания. Обзор посвящен систематизации результатов исследований генетических аспектов ОП и современным тенденциям дальнейшего изучения проблемы.
Об авторах
Р. Я. Миргалиева
Институт биохимии и генетики — обособленное структурное подразделение Федерального государственного бюджетного научного учреждения Уфимского федерального исследовательского центра Российской академии наук; ГБУЗ Республиканский медико-генетический центр
Россия
Россия
Э. К. Хуснутдинова
Институт биохимии и генетики — обособленное структурное подразделение Федерального государственного бюджетного научного учреждения Уфимского федерального исследовательского центра Российской академии наук
Россия
Россия
Р. И. Хусайнова
Институт биохимии и генетики — обособленное структурное подразделение Федерального государственного бюджетного научного учреждения Уфимского федерального исследовательского центра Российской академии наук
Россия
Россия
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Рецензия
Для цитирования:
Миргалиева Р.Я., Хуснутдинова Э.К., Хусайнова Р.И. ГЕНЕТИЧЕСКИЕ ОСНОВЫ ОСТЕОПОРОЗА. Медицинская генетика. 2018;17(7):3-10. https://doi.org/10.25557/2073-7998.2018.07.3-10
For citation:
Mirgaliyeva R.Y., Khusnutdinova E.K., Khusainova R.I. GENETIC BASIS OF OSTEOPOROSIS. Medical Genetics. 2018;17(7):3-10. (In Russ.) https://doi.org/10.25557/2073-7998.2018.07.3-10
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