The frequency of aneuploidy in sperm in men with impaired fertility

A. A. Tarlycheva; Zh. G. Markova; T. M. Sorokina; W. B. Chernyh; N. V. Shilova

doi:10.25557/2073-7998.2020.03.89-90

The frequency of aneuploidy in sperm in men with impaired fertility

A. A. Tarlycheva, Zh. G. Markova, T. M. Sorokina, W. B. Chernyh, N. V. Shilova

https://doi.org/10.25557/2073-7998.2020.03.89-90

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Abstract

Chromosomal abnormalities (CA), including aneuploidy, are one of the causes of spontaneous abortion, infertility, developmental disorders and malformations. One way to evaluate probability of aneuploid zygotes occurrence is the analysis of parental gametes, however, information about the level of aneuploidy in such cells is insufficient. There was evaluated the frequency of aneuploidy compatible with the viability of the zygote in sperm nuclei of 82 phenotypically normal infertile men with normal and impaired spermatogenesis.