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Correction of the embryonic karyotype at the preimplantation stage of human development

https://doi.org/10.25557/2073-7998.2020.03.49-50

Abstract

Comparative molecular karyotyping of cell-free DNA from the blastocoele fluid of the blastocyst and the embryoblast and trophectoderm, allowed us to obtain evidence for the presence of mechanisms of self-correction of the embryonic karyotype at the preimplantation stage of human development.

About the Authors

D. I. Zhigalina
Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS
Russian Federation


N. A. Skryabin
Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS
Russian Federation


O. R. Kanbekova
Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS
Russian Federation


V. G. Artyukhova
Krasnoyarsk Center for Reproductive Medicine, MD Medical Group «Mother and Child»
Russian Federation


A. V. Svetlakov
Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS
Russian Federation


I. N. Lebedev
Research Institute of Medical Genetics, Tomsk National Research Medical Center RAS
Russian Federation


Review

For citations:


Zhigalina D.I., Skryabin N.A., Kanbekova O.R., Artyukhova V.G., Svetlakov A.V., Lebedev I.N. Correction of the embryonic karyotype at the preimplantation stage of human development. Medical Genetics. 2020;19(3):49-50. (In Russ.) https://doi.org/10.25557/2073-7998.2020.03.49-50

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ISSN 2073-7998 (Print)