DESCRIPTIVE EPIDEMIOLOGY OF ESOPHAGEAL ATRESIA (DATA OF BIRTH DEFECTS MONITORING)
https://doi.org/10.1234/XXXX-XXXX-2015-1-25-31
Abstract
The paper presents the results of epidemiological studies of rare congenital malformation — esophageal atresia (EA). Data derived from birth defects monitoring during 2000—2012 in 30 regions of the Russian Federation. The total prevalence of AP for the entire observation period was 1.96 (95% C11.87—2.06) per 10 000 births or 1 case per 5099 births. The EA prevalence during the entire observation period remained stable. EA with tracheoesophageal fistula (TEF) represents 57.3% of the cases. In 68.2% of cases EA was isolated anomaly and associated malformations were present in 31.8%. Relative risk for EA was higher for the older maternal age group (RR is 1.51, 95% CI 1.25—1.84); for male (RR 1.22, 95% CI 1.08-to 1.38) and for infants with a birth weight less than 3,000 g (RR 4.82, 95% CI 4.24-5.48).
About the Authors
N. S. Demikova
Research Clinical Institute of Pediatrics of Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
Ju. V. Vydrych
I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation
Russian Federation
V. A. Podolnaya
Research Clinical Institute of Pediatrics of Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
A. S. Lapina
Research Clinical Institute of Pediatrics of Pirogov Russian National Research Medical University, Moscow
Russian Federation
Russian Federation
A. Ju. Asanov
I.M. Sechenov First Moscow State Medical University, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Demikova N.S., Vydrych J.V., Podolnaya V.A., Lapina A.S., Asanov A.J. DESCRIPTIVE EPIDEMIOLOGY OF ESOPHAGEAL ATRESIA (DATA OF BIRTH DEFECTS MONITORING). Medical Genetics. 2015;14(1):25-31. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2015-1-25-31
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