THE FREQUENCY OF ANEUPLOIDY IN SPERM OF INFERTILE MEN WITH PATHOZOOSPERMIA
https://doi.org/10.1234/XXXX-XXXX-2013-2-18-24
Abstract
FISH-analysis of sperm aneuploidy for chromosomes 13, 18, 21, X and Y was carried out for men with asthenoteratozoospermia and for men with vari ous severity of oligoasthenoteratozoospermia. Among the maj ority of exam i ned men and their wives infertil ity or habitual noncarrying of pregnancy were directional diagnoses. It was shown that high frequency of meiotic non-disjunction of chromosomes is attended to mild and moderate oligoasthenoteratozoospermia among men with infertil ity. The mean frequencies of spermatozoa with disomy for chromosomes 13, 18, 21, and XX, XY, YY disomy among patients with OAT I-III were 0,28%, 0,13%, 0,59%, 0,1%, 0,64% and 0,16%, respectively.
About the Authors
E. G. GordeevaRussian Federation
T. M. Sorokina
Russian Federation
L. V. Shileiko
Russian Federation
T. V. Ostroumova
Russian Federation
O. S. Borzova
Russian Federation
H. D. Magomedova
Russian Federation
N. Y. Kuzina
Russian Federation
O. V. Barkova
Russian Federation
L. F. Kurilo
Russian Federation
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Review
For citations:
Gordeeva E.G., Sorokina T.M., Shileiko L.V., Ostroumova T.V., Borzova O.S., Magomedova H.D., Kuzina N.Y., Barkova O.V., Kurilo L.F. THE FREQUENCY OF ANEUPLOIDY IN SPERM OF INFERTILE MEN WITH PATHOZOOSPERMIA. Medical Genetics. 2013;12(2):18-24. (In Russ.) https://doi.org/10.1234/XXXX-XXXX-2013-2-18-24