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Genetic aspects of the idiopathic form of habitual miscarriage

https://doi.org/10.25557/2073-7998.2020.11.83-84

Abstract

The first time made conducted study to determine the possible etiological condition of idiopathic forms of recurrent miscarriage by impaired immune interaction of maternal cells with syncytiotrophoblast, as well as by carriage of adverse risk alleles of the main HLA histocompatibility complex class 2.

About the Authors

G. S. Svyatova
The Scientific Center of Obstetrics, Gynecology and Perinatology
Russian Federation


G. M. Berezina
The Scientific Center of Obstetrics, Gynecology and Perinatology
Russian Federation


A. V. Murtazaliyeva
The Scientific Center of Obstetrics, Gynecology and Perinatology
Russian Federation


References

1. Manning A. K. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nature genetics. 2012; 44: 659-669.

2. Daher S., Mattar R., Gueuvoghlanian-Silva B. Y. Genetic polymorphisms and recurrent spontaneous abortions: an overview of current knowledge. Am. J. Reprod. Immunol. 2012; 67:.341-347.

3. Branch D. W., Gibson M., Silver R. M. Clinical practice. Recurrent miscarriage. N. Engl. J. Med. 2010; 363: 1740-1747.


Review

For citations:


Svyatova G.S., Berezina G.M., Murtazaliyeva A.V. Genetic aspects of the idiopathic form of habitual miscarriage. Medical Genetics. 2020;19(11):83-84. (In Russ.) https://doi.org/10.25557/2073-7998.2020.11.83-84

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ISSN 2073-7998 (Print)