The study of genetic and epigenetic factors in the development of osteoporosis
Abstract
Osteoporosis is one of the most common multifactorial diseases, which is characterized by a high risk of fractures and microarchitectural disorders of bone tissue. The study of genetic and epigenetic factors of this disease and their contribution to pathogenesis is relevant. We found the significance of the polymorphic variants rs11540149, rs6854081, rs10098470, rs10793442, rs1054204, rs3134069, rs3102734 and rs7844539 in increasing the risk of fractures and forming a low level of bone mineral density.
About the Authors
B. I. Yalaev
Institute of Biochemistry and Genetics of the Ufa Federal Research Centre RAS
Russian Federation
Russian Federation
R. I. Khusainova
Institute of Biochemistry and Genetics of the Ufa Federal Research Centre RAS
Russian Federation
Russian Federation
Review
For citations:
Yalaev B.I., Khusainova R.I. The study of genetic and epigenetic factors in the development of osteoporosis. Medical Genetics. 2020;19(8):65-66. (In Russ.)
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