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LIG1 and LIG3 repair gene polymorphisms and the risk of developing breast and ovarian cancer

Abstract

The nature of the effect on the formation of breast cancer and the reproductive system in 409 women with breast cancer and 60 with cancer in the Chechen population of four functionally significant polymorphisms of the LIG1 and LIG3 genes (rs156641, rs20579, rs1052536, rs4796030) was studied. Genotyping was performed using PCR analysis. We identified the candidate genotypes that influence the risk of developing breast and ovarian cancer.

About the Authors

Z. I. Bisultanova
Chechen State University
Russian Federation


P. M. Dzhambetova
Chechen State University
Russian Federation


Review

For citations:


Bisultanova Z.I., Dzhambetova P.M. LIG1 and LIG3 repair gene polymorphisms and the risk of developing breast and ovarian cancer. Medical Genetics. 2020;19(6):38-39. (In Russ.)

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This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2073-7998 (Print)