Chromosomal abnormalities in the first-trimester fetuses with abdominal cysts

Abstract

First-trimester aborted fetuses with abdominal cysts (n=76) have been examined at anatomic-pathological investigation. A final diagnosis included choledochal cyst, duodenal and anorectal atresia, cloacal disgenesis syndrome and megacystis. Besides gastrointestinal atresia and lower urinary tract obstructions heterotaxy and diaphragmatic hernia have been revealed at morphological examination. In total 23,7% of fetal abdominal cysts in the first trimester of gestation were associated with chromosomal abnormalities.