Preimplantation genetic testing for aneuploidy: state of the art, trends and perspectives
https://doi.org/10.25557/2073-7998.2019.03. 3-12
Abstract
Prevention of chromosomal diseases through preimplantation genetic testing is an edge issue of current reproductive medicine and genetics. Embryo testing during in vitro fertilization cycles is designed to eliminate the transfer of aneuploid blastocysts, providing an increased probability of the take home babies, as well as reducing the risks of reproductive losses due to chromosomal abnormalities. The current state of the preimplantation genetic testing, its trends and perspectives are discussed.
Keywords
анеуплоидия,
преимплантационная генетическая диагностика,
преимплантационный генетический скрининг,
преимплантационное генетическое тестирование,
хромосомные болезни,
хромосомный мозаицизм,
экстракорпоральное оплодотворение,
aneuploidy,
in vitro fertilization,
preimplantation genetic diagnosis,
preimplantation genetic screening,
preimplantation genetic testing for aneuploidy (PGT-A),
chromosomal diseases,
chromosomal mosaicism
About the Author
I. N. Lebedev
Research Institute of Medical Genetics Tomsk National Research Medical Center of the Russian Academy of Science
Russian Federation
Russian Federation
Review
For citations:
Lebedev I.N. Preimplantation genetic testing for aneuploidy: state of the art, trends and perspectives. Medical Genetics. 2019;18(3):3-12. (In Russ.) https://doi.org/10.25557/2073-7998.2019.03. 3-12
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