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Dynamics of gene pool of Moscow population under action of migration processes.
https://doi.org/10.25557/2073-7998.2025.12.148-150
Abstract
In megalopolis, dynamics of the gene pool is mediated by unequal natural increase of ethnic groups and variable migration processes. Prognosis of dynamics of the gene pool of megalopolis under action of genetic demographic processes is actual for ensuring demographic and genetic security of population. Using data of demographic statistics and questionnaire data of residents, parameters of migration and spectrum of ethnic groups in the migration flows to megalopolis were studied. In three generations of Moscow residents, haplogroups of Y-chromosome were predicted by means of Internet-predictor Whit Athley’s by 18 STR of Y-chromosome. Taking into account intensity of migration flows and ethnoterritorial composition of migrants arriving in the megalopolis, long-term prognosis was performed for dynamics of haplogroups of Y-chromosome. Technique applied for compilation of the genetic prognosis is universal, and might be used for any genetic markers, including markers of hereditary diseases.
Keywords
megalopolis,
migration,
gene pool,
dynamics,
STR,
haplotypes,
Y-chromosome,
haplogroups,
reference database
Supporting agencies: The research was carried out within the framework of the N.I. Vavilov Institute of General Genetics, RAS State task: «The study of genetic polymorphism of cell, organism and population for development new genetic technologies».
About the Authors
I. G. Udina
N.I. Vavilov Institute of General Genetics of the Russian Academy of Sciences
Россия
Россия
A. S. Gracheva
N.I. Vavilov Institute of General Genetics of the Russian Academy of Sciences
Россия
Россия
References
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Review
For citations:
Udina I.G., Gracheva A.S. Dynamics of gene pool of Moscow population under action of migration processes. Medical Genetics. 2025;24(12):148-150. (In Russ.) https://doi.org/10.25557/2073-7998.2025.12.148-150
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