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The frequency of variants of the MEFV gene responsible for the development of periodic disease in Dagestan residents
https://doi.org/10.25557/2073-7998.2025.11.19-26
Abstract
Familial Mediterranean fever (FMF) has a certain ethnic specificity. Some ethnic groups inhabiting the Republic of Dagestan have a common origin with the Mediterranean populations in which FMF is widespread. A survey of 390 representatives of the indigenous ethnic groups of Dagestan was conducted, and the frequencies of variants in the MEFV gene were determined.
Keywords
Supporting agencies: The authors declare no conflict of interests
About the Authors
D. V. Lendoeva
Research Centre for Medical Genetics
Russian Federation
Russian Federation
Darina V. Lendoeva
1, Moskvorechye st., Moscow, 115522
V. A. Kadnikova
Research Centre for Medical Genetics
Russian Federation
Russian Federation
1, Moskvorechye st., Moscow, 115522
A. V. Polyakov
Research Centre for Medical Genetics
Russian Federation
Russian Federation
1, Moskvorechye st., Moscow, 115522
G. M. Radzhabova
IMC International Medical Center; Dagestan Federal Research Center of the Russian Academy of Sciences
Russian Federation
Russian Federation
73, Atsi Abdullayeva st., Makhachkala, 367010; 94, M.Yaragskogo st., Makhachkala, 367030
M. O. Radzhabov
IMC International Medical Center; Dagestan Federal Research Center of the Russian Academy of Sciences
Russian Federation
Russian Federation
73, Atsi Abdullayeva st., Makhachkala, 367010; 94, M.Yaragskogo st., Makhachkala, 367030
O. A. Shchagina
Research Centre for Medical Genetics
Russian Federation
Russian Federation
1, Moskvorechye st., Moscow, 115522
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Review
For citations:
Lendoeva D.V., Kadnikova V.A., Polyakov A.V., Radzhabova G.M., Radzhabov M.O., Shchagina O.A. The frequency of variants of the MEFV gene responsible for the development of periodic disease in Dagestan residents. Medical Genetics. 2025;24(11):19-26. (In Russ.) https://doi.org/10.25557/2073-7998.2025.11.19-26
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