medgenМедицинская генетикаMedical Genetics2073-7998Publishing House «Genius Media» LLC10.25557/2073-7998.2025.11.19-26medgen-3292Research ArticleОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕORIGINAL ARTICLEЧастота вариантов гена MEFV, ответственных за развитие периодической болезни у жителей ДагестанаThe frequency of variants of the MEFV gene responsible for the development of periodic disease in Dagestan residentsЛендоеваД. В.LendoevaD. V.

Лендоева Дарина Викторовна

115522, Москва, ул. Москворечье, д.1

Darina V. Lendoeva

1, Moskvorechye st., Moscow, 115522

auquel1002@yandex.ruКадниковаВ. А.KadnikovaV. A.

115522, Москва, ул. Москворечье, д.1

1, Moskvorechye st., Moscow, 115522

ПоляковА. В.PolyakovA. V.

115522, Москва, ул. Москворечье, д.1

1, Moskvorechye st., Moscow, 115522

РаджабоваГ. М.RadzhabovaG. M.

367010, Махачкала, ул. Ацы Абдуллаева, д. 73

73, Atsi Abdullayeva st., Makhachkala, 367010; 94, M.Yaragskogo st., Makhachkala, 367030

РаджабовМ. О.RadzhabovM. O.

367030, Махачкала, ул. М. Ярагского, д. 94,

73, Atsi Abdullayeva st., Makhachkala, 367010; 94, M.Yaragskogo st., Makhachkala, 367030

ЩагинаО. А.ShchaginaO. A.

115522, Москва, ул. Москворечье, д.1

1, Moskvorechye st., Moscow, 115522

ФГБНУ «Медико-генетический научный центр имени академика Н.П. Бочкова»РоссияResearch Centre for Medical GeneticsRussian FederationМеждународный медицинский центр IMРоссияIMC International Medical Center; Dagestan Federal Research Center of the Russian Academy of SciencesRussian FederationДагестанский федеральный исследовательский центр РАНРоссияIMC International Medical Center; Dagestan Federal Research Center of the Russian Academy of SciencesRussian Federation20252412202524111926Copyright © Лендоева Д.В., Кадникова В.А., Поляков А.В., Раджабова Г.М., Раджабов М.О., Щагина О.А., 20252025Лендоева Д.В., Кадникова В.А., Поляков А.В., Раджабова Г.М., Раджабов М.О., Щагина О.А.Lendoeva D.V., Kadnikova V.A., Polyakov A.V., Radzhabova G.M., Radzhabov M.O., Shchagina O.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medgen-journal.ru/jour/article/view/3292

Семейная средиземноморская лихорадка (СCЛ) имеет определенную этническую специфику. Некоторые этнические группы, населяющие Республику Дагестан, имеют общее происхождение со средиземноморскими популяциями, в которых широко распространена ССЛ. Проведено обследование 390 представителей коренных этносов Дагестана, определены частоты вариантов в гене MEFV.

Familial Mediterranean fever (FMF) has a certain ethnic specificity. Some ethnic groups inhabiting the Republic of Dagestan have a common origin with the Mediterranean populations in which FMF is widespread. A survey of 390 representatives of the indigenous ethnic groups of Dagestan was conducted, and the frequencies of variants in the MEFV gene were determined.

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The authors declare that there are no conflicts of interest present.