Generate QR code
Open Access
Subscription Access
Analysis of the marital structure of married couples with genetic screening for carriage of hereditary diseases
https://doi.org/10.25557/2073-7998.2025.09.36-37
Abstract
The marriage structure of married couples was studied during reproductive genetic screening for carriage of hereditary diseases. The marriage structure was assessed based on the data on the ethnicity and place of birth of the spouses. Marriage migration processes are limited to the territory of Yakutia. Monoethnic Yakut marriages are most common. A positive value of marriage assortativity was obtained among the Yakuts. A high frequency of heterozygous carriage of autosomal recessive diseases was revealed. Genetic screening throughout the republic is necessary for their prevention.
Supporting agencies: The study was carried out under the state assignment of the Ministry of Science and Higher Education of the Russian Federation «Genomics of the Arctic: diagnostics, prevention and treatment» (FSRG-2024-0001).
About the Authors
A. L. Danilova
North-Eastern Federal University
Russian Federation
Russian Federation
58, Belinsky st., Yakutsk, 677000
A. L. Sukhomyasova
North-Eastern Federal University
Russian Federation
Russian Federation
58, Belinsky st., Yakutsk, 677000
N. R. Maksimova
North-Eastern Federal University
Russian Federation
Russian Federation
58, Belinsky st., Yakutsk, 677000
References
1. Nariman A., Sobhan M.R., Savaei M et al. The genetic background of Southern Iranian couples before marriage. BJMG, 2016;19(2):71- 74. https:// doi:10.1515/bjmg-2016-0038.
2. Zaitlen N., Huntsman S., Hu D. et al. The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium. Genetics, 2017;205(1):375-383. https:// doi:10.1534/genetics.116.192138.
3. Kirikbayeva M.S., Baiusbekova A.G., Berezina G.M. et al. Ethnic assortativeness and intensity of miscegenation of the kazakhstan uigurs. Vestnik Moskovskogo universiteta. Seriya XXIII. Antropologiya [Bulletin of the Moscow University. Series XXIII. Anthropology]. 2011;1:84-87. (In Russ.)
4. Eremina E.R., Kucher A.N. Etnicheskaya assortativnost’ brakov v gorode Ulan-Ude [Ethnic marriage assortative mating in Uhlan-Ude]. Socialnaya gigiena i organizaciya zdravoohraneniya [Social hygiene and healthcare organization]. 2010;30(6):110-117. (In Russ.)
5. Kurbatova O.L. Genetiko-demograficheskij analiz mezhetnicheskih razlichij reproduktivnogo povedeniya [The Genetic-demographic analysis of interethnic distinctions of reproductive behavior]. Ashkhabad, 1991:21. (In Russ.)
Review
For citations:
Danilova A.L., Sukhomyasova A.L., Maksimova N.R. Analysis of the marital structure of married couples with genetic screening for carriage of hereditary diseases. Medical Genetics. 2025;24(9):36-37. (In Russ.) https://doi.org/10.25557/2073-7998.2025.09.36-37
Views:
14
Email this article 