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Analysis of single nucleotide polymorphism of genes of the blood coagulation system FV (G1691A), ITGA2 (C807T) in patients with miscarriage

https://doi.org/10.25557/2073-7998.2025.08.137-139

Abstract

   The article reports findings from a molecular genetic analysis conducted on women experiencing habitual miscarriage. The study evaluated the frequency of single nucleotide polymorphisms in the FV (G1691A) and ITGA2 (C807T) genes within the sample population. The results indicated that the heterozygous variant of the ITGA2 (C807T) gene was the most prevalent among the participants, whereas the heterozygous variant of the FV (G1691A) gene was observed less frequently. Notably, the occurrence of mutant homozygotes was not identified in this cohort.

About the Authors

V. V. Shеvtsova
Kursk Regional Multidisciplinary Clinical Hospital
Russian Federation

Vera V. Shеvtsova

305007; 45-а, Sumskaya st.; Kursk



G. V. Komkova
Kursk State Medical University
Russian Federation

305041; 3, K. Marx st.; Kursk



References

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Review

For citations:


Shеvtsova V.V., Komkova G.V. Analysis of single nucleotide polymorphism of genes of the blood coagulation system FV (G1691A), ITGA2 (C807T) in patients with miscarriage. Medical Genetics. 2025;24(8):137-139. (In Russ.) https://doi.org/10.25557/2073-7998.2025.08.137-139

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ISSN 2073-7998 (Print)