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Current challenges of genotoxicity testing

https://doi.org/10.25557/2073-7998.2025.07.37-39

Abstract

There are two challenges that need to be addressed today in the genotoxicity testing. The first one includes improvement of in vitro testing methodology and development of high-throughput test systems for genotoxicity screening. The second one is determined by the necessity to develop new methods to register gene mutations in vivo, including genotoxicity in germ cells. Current methodological achievements promising for solving the above tasks are considered.

About the Authors

A. K. Zhanataev
Federal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies
Russian Federation

8, Baltiyskaya st., Moscow, 125315



A. D. Durnev
Federal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies
Russian Federation

8, Baltiyskaya st., Moscow, 125315



References

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Review

For citations:


Zhanataev A.K., Durnev A.D. Current challenges of genotoxicity testing. Medical Genetics. 2025;24(7):37-39. (In Russ.) https://doi.org/10.25557/2073-7998.2025.07.37-39

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ISSN 2073-7998 (Print)