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Study of the effect of chemical bacterial cell proteome using Lux biosensors
https://doi.org/10.25557/2073-7998.2025.04.12-13
Abstract
Heat shock proteins, which perform the functions of chaperones, contribute to the process of de novo folding of synthesized proteins and refolding of denatured proteins. It has been shown that mutagens formaldehyde, sodium azide, and potassium bichromate cause disturbances in protein structures, which was recorded by the luminescence of biosensors based on the E. coli strain K12 MG1655, which luminesce in response to the appearance of structurally disturbed proteins in the cell.
About the Authors
S. K. Abilev
N.I. Vavilov Institute of General Genetics of Russian Academic Science
Russian Federation
Russian Federation
Serikbai K. Abilev
3, Gubkina st., Moscow, 119991
S. V. Smirnova
N.I. Vavilov Institute of General Genetics of Russian Academic Science
Russian Federation
Russian Federation
3, Gubkina st., Moscow, 119991
A. G. Kurkieva
N.I. Vavilov Institute of General Genetics of Russian Academic Science
Russian Federation
Russian Federation
3, Gubkina st., Moscow, 119991
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Review
For citations:
Abilev S.K., Smirnova S.V., Kurkieva A.G. Study of the effect of chemical bacterial cell proteome using Lux biosensors. Medical Genetics. 2025;24(4):12-13. (In Russ.) https://doi.org/10.25557/2073-7998.2025.04.12-13
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