Genetic diversity and identification information content of 43 autosomal STR markers in Avarian populations
https://doi.org/10.25557/2073-7998.2023.12.52-58
Abstract
We assessed the level of genetic diversity, power of discrimination, power of exclusion of 43 autosomal STRs (D3S1358, TH01, D12S391, D5S818, TPOX, D13S317, FGA, D22S1045, D18S51, D16S539 , D8S1179, CSF1PO, D6S1043, vWA, D21S11, SE33, D10S1248, D1S1656, D19S433, D2S1338, D20S1082, D6S474, D12ATA63, D4S2666, D1S1677, D11S4463, D9S1 122, D2S1776, D10S1435, D3S3053, D5S2500, D1S1627, D3S4529, D2S1360, D17S974 , D3S1744, D9S2157, D17S1301, D8S1132, Penta D, D21S2050, D7S1517, Penta E) in Avar populations from three regions of Dagestan: Shamilsky district, Tlyaratinsky district, Untsukulsky district. The results emphasized the need to take into account the geographic origin of the individual, and not just his nationality, when choosing reference data during genetic examination in the populations of Dagestan.
About the Authors
K. V. Vagaitseva
Research Institute of Medical Genetics, Tomsk NRMC
Russian Federation
Russian Federation
10, Naberejnaya Ushaiki, Tomsk, 634050
N. A. Kolesnikov
Research Institute of Medical Genetics, Tomsk NRMC
Russian Federation
Russian Federation
10, Naberejnaya Ushaiki, Tomsk, 634050
M. D. Skalin
Vavilov Institute of General Genetics Russian Academy of Sciences
Russian Federation
Russian Federation
3, Gubkina st., Moscow, 119333
V. N. Kharkov
Research Institute of Medical Genetics, Tomsk NRMC
Russian Federation
Russian Federation
10, Naberejnaya Ushaiki, Tomsk, 634050
M. O. Radzhabov
Institute of Physics. HI Amirkhanova Dagestan Scientific Center, Russian Academy of Sciences
Russian Federation
Russian Federation
94, M. Yaragskogo st., Makhachkala, 367015
V. A. Stepanov
Research Institute of Medical Genetics, Tomsk NRMC
Russian Federation
Russian Federation
10, Naberejnaya Ushaiki, Tomsk, 634050
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Review
For citations:
Vagaitseva K.V., Kolesnikov N.A., Skalin M.D., Kharkov V.N., Radzhabov M.O., Stepanov V.A. Genetic diversity and identification information content of 43 autosomal STR markers in Avarian populations. Medical Genetics. 2023;22(12):52-58. (In Russ.) https://doi.org/10.25557/2073-7998.2023.12.52-58
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