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Медицинская генетика

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Современные представления о генетике остеоартроза

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Аннотация

В представленном обзоре отражены современные достижения в исследовании генетики остеоартроза - широко распространенного прогрессирующего заболевания суставов неизвестной этиологии, характеризующегося поражением всех компонентов сустава и приводящего к затруднению движения, снижению качества жизни и инвалидизации больных. Рассматриваются ключевые вопросы молекулярного патогенеза заболевания, включая генетические и эпигенетические аспекты, а также существующие проблемы в данной области исследований.

Об авторах

Д. А. Шаповалова
Институт биохимии и генетики Уфимского научного центра Российской академии наук
Россия


А. В. Тюрин
Институт биохимии и генетики Уфимского научного центра Российской академии наук
Россия


Э. К. Хуснутдинова
Институт биохимии и генетики Уфимского научного центра Российской академии наук
Россия


Р. И. Хусаинова
Институт биохимии и генетики Уфимского научного центра Российской академии наук
Россия


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Для цитирования:


Шаповалова Д.А., Тюрин А.В., Хуснутдинова Э.К., Хусаинова Р.И. Современные представления о генетике остеоартроза. Медицинская генетика. 2017;16(2):3-10.

For citation:


Shapovalova D.A., Tyurin A.V., Khusnutdinova E.K., Khusainova R.I. Recent advances in genetics of osteoarthritis. Medical Genetics. 2017;16(2):3-10. (In Russ.)

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