Significance of polymorphic variants of the renin-angiotensin system, pro-oxidant-antioxidant system and vascular endothelial growth factor as genetic predictors of preeclampsia
https://doi.org/10.25557/2073-7998.2020.11.76-78
Abstract
In the search for genetic risk factors for preeclampsia, the role of polymorphic variants of key genes of the renin-angiotensin system, pro-oxidant-antioxidant system, and vascular endothelial growth factor was studied, possibly forming its main clinical manifestations: increased blood pressure, placental oxidative stress, and endothelial vascular dysfunction in the «mother-placenta-fetus» circulatory system. Reliable genetic predictors of this pregnancy complication have been determined.
About the Authors
L. V. Akulenko
Moscow State Medical and Dental University named after A.I.Evdokimov of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
N. Y. Sakvarelidze
Moscow State Medical and Dental University named after A.I.Evdokimov of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
S. G. Tsakhilova
Moscow State Medical and Dental University named after A.I.Evdokimov of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Akulenko L.V., Sakvarelidze N.Y., Tsakhilova S.G. Significance of polymorphic variants of the renin-angiotensin system, pro-oxidant-antioxidant system and vascular endothelial growth factor as genetic predictors of preeclampsia. Medical Genetics. 2020;19(11):76-78. (In Russ.) https://doi.org/10.25557/2073-7998.2020.11.76-78
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