Molecular response of human skin fibroblasts with a mutation m. 14441 T>C on the action of ionizing radiation in low and medium doses

Abstract

Fibroblasts with the mutation of m.14441 T>C in the ND6 gene and fibroblasts of a healthy donor were chosen as a research model. It was shown that this mutation in the ND6 mitochondrial DNA gene has a significant effect on the cellular response during oxidative stress.