Еffect of different antioxidant drug on the level of dna-damage and redox potential of cells of spermatogenous tissue

Abstract

The effect of mexidol, dihydroquercetin, dibornol and paratyrosol on the amount of DNA damage and the redox potential in rat testicular tissue cells was studied. It was established, that all studied compounds, except mexidol, reduced the number of DNA breaks in the cells and had a normalizing effect on their redox potential under the conditions of DNA damage to spermatogenic tissue cells. The highest therapeutic activity was detected in dihydroquercetin.