The study of the genetic component of eating behavior in a sample of obese Yakuts

Abstract

The nature of the nutrition of the inhabitants of the North is from lipo-lipid. Among them, the number of obese people increased, due not only to the variable nature of nutrition, but also to physical inactivity. The aim of the study is to study the genetic component of eating disorders. In total, 191 people took part in the study, of which 100 people suffer from obesity of varying severity (73 women and 27 men), which allows us to compare a sample of people with normal MMT ((25) in the amount of 91 people (70 women and 21 men). According to the results of studies, the frequency of occurrence of the mutant allele A of rs9939609 FTO gene in all the studied groups is 27%, while the AA genotype is only 9.4%. An analysis of the distribution of alleles and genotypes of rs27072 polymorphism of the DAT1 gene showed the predominance of the ancestral G allele (90.8%) and the GG genotype (82.7%) in all examined samples.