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Investigation of non-coding RNA gene polymorphisms LINC02952/LINC02953, LINC02747/LINC02952, LINC02664 in clear cell renal cell carcinoma patients
https://doi.org/10.25557/2073-7998.2025.07.123-125
Abstract
Сlear cell renal cell carcinoma (ccRCC) is a heterogeneous aggressive disease with a high mortality rate, so the search for risk markers is a relevant task. The material for the study was 128 DNA samples of ccRCC patients and 134 healthy individuals. It was revealed that the risk markers for ccRCC are rs11263432*T and rs793096*T alleles (OR=2.32 (95%CI=1.1–5.3) p=0.04 and OR=1.49 (95%CI=1.0-2.1) p=0.035, respectively).
Supporting agencies: The work was performed within the framework of the State Assignment (№1022040500074-9) of the IBG UFRC RAS.
About the Authors
A. K. Chumakova
Ufa Federal Research Center of the Russian Academy of Sciences, Institute of Biochemistry and Genetics
Russian Federation
Russian Federation
71, Prospekt Oktyabrya st., Ufa, 450054
I. R. Gilyazova
Ufa Federal Research Center of the Russian Academy of Sciences, Institute of Biochemistry and Genetics;
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
71, Prospekt Oktyabrya st., Ufa, 450054;
3, Lenina st., Ufa, 450008
A. A. Izmaylov
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
3, Lenina st., Ufa, 450008
E. A. Ivanova
Ufa Federal Research Center of the Russian Academy of Sciences, Institute of Biochemistry and Genetics
Russian Federation
Russian Federation
71, Prospekt Oktyabrya st., Ufa, 450054
M. A. Bermisheva
Ufa Federal Research Center of the Russian Academy of Sciences, Institute of Biochemistry and Genetics;
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
71, Prospekt Oktyabrya st., Ufa, 450054;
3, Lenina st., Ufa, 450008
G. R. Abdeeva
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
3, Lenina st., Ufa, 450008
V. N. Pavlov
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
3, Lenina st., Ufa, 450008
E. K. Khusnutdinova
Ufa Federal Research Center of the Russian Academy of Sciences, Institute of Biochemistry and Genetics;
Bashkir State Medical University, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
71, Prospekt Oktyabrya st., Ufa, 450054;
3, Lenina st., Ufa, 450008
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Review
For citations:
Chumakova A.K., Gilyazova I.R., Izmaylov A.A., Ivanova E.A., Bermisheva M.A., Abdeeva G.R., Pavlov V.N., Khusnutdinova E.K. Investigation of non-coding RNA gene polymorphisms LINC02952/LINC02953, LINC02747/LINC02952, LINC02664 in clear cell renal cell carcinoma patients. Medical Genetics. 2025;24(7):123-125. (In Russ.) https://doi.org/10.25557/2073-7998.2025.07.123-125
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