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Genetic structure of early morbid obesity in children in the Russian Federation
https://doi.org/10.25557/2073-7998.2025.07.32-33
Abstract
The clinical characteristics were assessed and a genetic cause was sought in 126 patients (55 girls and 71 boys) with obesity (SDS BMI>3.0) at an early age (up to 7 years). The median age of patients at the time of examination was 9.2 years. Nucleotide sequence changes in 37 genes were detected in 49.7% of children. In patients with obesity of unknown cause, a burdened hereditary history of obesity was statistically significantly more common than in patients with genetic disorders (p<0.001).
Supporting agencies: The study conducted with the support provided by the «CAF» Fund for the Support and Development of Philanthropy and with budgetary funds from the healthcare institution participating in the study (Endocrinology Research Centre).
About the Authors
O. V. Vasyukova
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
D. A. Kopytina
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
P. L. Okorokov
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
R. R. Salakhov
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
R. I. Khusainova
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
I. R. Minniakhmetov
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
E. V. Nagaeva
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
O. B. Bezlepkina
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
V. A. Peterkova
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
N. G. Mokrysheva
Endocrinology Research Centre
Russian Federation
Russian Federation
11, Dmitry Ulyanov st., Moscow, 117292
References
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Review
For citations:
Vasyukova O.V., Kopytina D.A., Okorokov P.L., Salakhov R.R., Khusainova R.I., Minniakhmetov I.R., Nagaeva E.V., Bezlepkina O.B., Peterkova V.A., Mokrysheva N.G. Genetic structure of early morbid obesity in children in the Russian Federation. Medical Genetics. 2025;24(7):32-33. (In Russ.) https://doi.org/10.25557/2073-7998.2025.07.32-33
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