Preview

Medical Genetics

Advanced search
Open Access Open Access  Restricted Access Subscription Access

Southern Altaians: the difference in the structure of the gene pool of Telengites and Altai-Kizhi according to X-STR markers

https://doi.org/doi.org/10.25557/2073-7998.2024.06.44-47

Abstract

The brief report presents the results of the analysis of genetic diversity and the structure of linkage disequilibrium in two populations of southern Altaians: Telengites and Altai-Kizhi. The analysis was performed using the TYPER X-19 multiplex set, which includes 18 STR markers localized on the X chromosome. The specificity of the genetic structure of the two ethnic groups is demonstrated, and differences in the structure of linkage disequilibrium are revealed. The assessment of the level of identification informativeness of 18 X-STR for DNA identification was carried out.

About the Authors

K. V. Vagaytseva
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



L. V. Valikhova
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



N. A. Kolesnikov
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



V. N. Kharkov
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



A. V. Bocharova
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



I. A. Volkova
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



V. A. Stepanov
Research Institute of Medical Genetics, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

10, Ushaika st., Tomsk 634050



References

1. Алтайцы: Этническая история. Традиционная культура. Современное развитие». Редколл. Н.В. Екеев (отв. ред.), Н.М. Екеева, Э.В. Енчинов; НИИ алтаистики им. С.С. Суразакова. – Горно-Алтайск: Горно-Алт. тип., 2014. – 464 с.

2. Kharkov V.N., Stepanov V.A., Medvedeva O.F., Spiridonova M.G., Puzyrev V.P., Voevoda M.I., Tadinova V.N. Gene pool differences between Northern and Southern Altaians inferred from the data on Y-chromosomal haplogroups. Russian Journal of Genetics. 2007; 43(5): 551-562. DOI: 10.1134/S1022795407050110

3. Балаганская О.А., Балановская Е.В., Лавряшина М.Б. и др. Полиморфизм Y хромосомы у тюркоязычного населения Алтае-Саян, Тянь-Шаня и Памира в контексте взаимодействия генофондов западной и восточной Евразии. Медицинская генетика. 2011; 3(105):12-22.

4. Kolesnikov N.A., Kharkov V.N., Zarubin A.A., Radzhabov M.O. et al. Features of the Genomic Distribution of Runs of Homozygosity in the Indigenous Population of Northern Eurasia at the Individual and Population Levels Based on High Density SNP Analysis. Russian Journal of Genetics. 2021; 57(11): 1271-1284

5. Лавряшина М.Б., Ульянова М.В., Балаганская А.Г. и др. Генетический портрет десяти малых народов Южной Сибири. Сообщение II. Гетерозиготность и подразделенность генофонда по данным об аутосомных ДНК-маркерах. Медицинская генетика. 2010; 9:16-23.

6. Zhang Y., Yu Z., Mo X. et al. Development and validation of a new 18 X-STR typing assay for forensic applications. Electrophoresis. 2021; 42(6):766-773.

7. База данных ChrX-STR.org 2.0 [Электронный ресурс] https://www.chrx-str.org/xdb/index.jsf Дата последнего обращения 03.05.2024

8. Excoffier, L., H.E. L. Lischer Arlequin suite ver 3.5: A new series of programs to perform population genetics analyses under Linux and Windows. Molecular Ecology Resources. 2010; 10: 564-567.

9. Rohlfs R.V., Fullerton S.M., Weir B.S. Familial identification: population structure and relationship distinguishability. PLoS Genet. 2012; 8(2): e1002469.


Review

For citations:


Vagaytseva K.V., Valikhova L.V., Kolesnikov N.A., Kharkov V.N., Bocharova A.V., Volkova I.A., Stepanov V.A. Southern Altaians: the difference in the structure of the gene pool of Telengites and Altai-Kizhi according to X-STR markers. Medical Genetics. 2024;23(6):44-47. (In Russ.) https://doi.org/doi.org/10.25557/2073-7998.2024.06.44-47

Views: 242


ISSN 2073-7998 (Print)