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The role of exon II HTR2A transcript isoforms in the development of mental pathologies and antipsychotic therapy prognosis
https://doi.org/10.25557/2073-7998.2020.04.24-26
Abstract
The aim of the study was to analyze the role of exon II HTR2A gene transcript isoforms and rs6311 genetic variant in the development of mental pathologies and antipsychotic therapy prognosis. Alternative isoforms of exon II HTR2A are associated with the development of mental pathologies and is applicable to predict antipsychotic therapy outcome.
About the Authors
M. N. Grunina
Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre «Kurchatov Institute»
Russian Federation
Russian Federation
A. M. Zabotina
Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre «Kurchatov Institute»
Russian Federation
Russian Federation
A. S. Zhuravlev
Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre «Kurchatov Institute»
Russian Federation
Russian Federation
R. F. Nasyrova
V.M. Bekhterev National Medical Research Center Psychiatry and Neurology
Russian Federation
Russian Federation
A. E. Taraskina
Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre «Kurchatov Institute»
Russian Federation
Russian Federation
Review
For citations:
Grunina M.N., Zabotina A.M., Zhuravlev A.S., Nasyrova R.F., Taraskina A.E. The role of exon II HTR2A transcript isoforms in the development of mental pathologies and antipsychotic therapy prognosis. Medical Genetics. 2020;19(4):24-26. (In Russ.) https://doi.org/10.25557/2073-7998.2020.04.24-26
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