medgenМедицинская генетикаMedical Genetics2073-7998Publishing House «Genius Media» LLC10.1234/XXXX-XXXX-2016-1-3-13medgen-86Research ArticleНАУЧНЫЕ ОБЗОРЫREVIEWГенетика мигрениGenetics of migraineКондратьеваН. С.KondratievaN. S.noemail@neicon.ruАнучинаА. А.AnuchinaA. A.noemail@neicon.ruКокаеваЗ. Г.KokaevaZ. G.noemail@neicon.ruНаумоваЕ. А.NaumovaE. A.noemail@neicon.ruАзимоваЮ. Э.AzimovaJ. E.noemail@neicon.ruСергеевА. В.SergeevA. V.noemail@neicon.ruСкоробогатыхК. В.SkorobogatykhK. V.noemail@neicon.ruТабееваГ. Р.TabeevaG. R.noemail@neicon.ruКлимовЕ. А.KlimovE. A.klimov_eugeney@mail.ruФГБОУ ВПО «Московский государственный университет им. М.В.Ломоносова»РоссияLomonosov Moscow State UniversityRussian FederationУниверситетская клиника головной боли; ФГБУ «Российский научный центр медицинской реабилитации и курортологии»РоссияUniversity Headache ClinicRussian FederationУниверситетская клиника головной боли; ГБОУ ВПО "Первый Московский государственный медицинский университет им. И.М. Сеченова"РоссияUniversity Headache ClinicRussian FederationУниверситетская клиника головной болиРоссияUniversity Headache ClinicRussian FederationФГБОУ ВПО «Московский государственный университет им. М.В.Ломоносова»; ООО «Университетская диагностическая лаборатория»РоссияLomonosov Moscow State UniversityRussian Federation201607102016151313Copyright © Кондратьева Н.С., Анучина А.А., Кокаева З.Г., Наумова Е.А., Азимова Ю.Э., Сергеев А.В., Скоробогатых К.В., Табеева Г.Р., Климов Е.А., 20162016Кондратьева Н.С., Анучина А.А., Кокаева З.Г., Наумова Е.А., Азимова Ю.Э., Сергеев А.В., Скоробогатых К.В., Табеева Г.Р., Климов Е.А.Kondratieva N.S., Anuchina A.A., Kokaeva Z.G., Naumova E.A., Azimova J.E., Sergeev A.V., Skorobogatykh K.V., Tabeeva G.R., Klimov E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medgen-journal.ru/jour/article/view/86

В настоящее время мигрень занимает 9-е место в списке ведущих причин нетрудоспособности населения. В России распространённость мигрени почти в два раза превышает мировые показатели и наносит немалый ущерб экономике государства. Несмотря на почти вековую историю изучения мигрени, наука до сих пор не может объяснить многие случаи возникновения приступов. Это вызывает затруднения и при постановке диагноза, и при лечении - терапия пациентов с мигренью недостаточно эффективна. Одним из направлений исследований сегодня является поиск биомаркёров мигрени, подтверждающих диагноз. В данном обзоре мы попытались обобщить имеющиеся на сегодняшний день результаты работ, направленных на поиск генетических маркёров мигрени.

Today migraine takes 9th place in the list of main reasons of population disability. In Russia migraine prevalence is two times higher than world index; in addition, the disease causes large damage to state economics. Despite almost one-century history of studying migraine, science until now can’t explain many cases of attack occurrence. It causes difficulties also in diagnosis determination and in treatment - the therapy of patients with migraine isn’t sufficiently effective. Today one of the investigation directions is searching of migraine biomarkers confirming diagnosis. In this review we attempted to generalize results of available up to date works direct on genetic markers of migraine searching.

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The authors declare that there are no conflicts of interest present.