References

medgen

Медицинская генетика

Medical Genetics

2073-7998

Publishing House «Genius Media» LLC

10.1234/XXXX-XXXX-2013-4-3-7

medgen-44

Research Article

НАУЧНЫЕ ОБЗОРЫ

REVIEW

ГЕНЕТИЧЕСКИЕ ОСНОВЫ ГЕМИПЛЕГИЧЕСКОЙ МИГРЕНИ

HEMIPLEGIC MIGRAINE

Азимова

Ю. Э.

Azimova

J. E.

Климов

Е. А.

Klimov

Е. А.

Скоробогатых

К. В.

Skorobogatykh

K. V.

Сергеев

А. В.

Sergeev

А. V.

Кокаева

З. Г.

Kokaeva

Z. G.

Табеева

Г. Р.

Tabeeva

G. R.

Лаборатория неврологии и клинической нейрофизиологии НИЦ Первого МГМУ им. И.М. Сеченова, Москва; Университетская клиника головной боли, МоскваРоссияLaboratory of Neurology and Clinical Neurophysiology, Department of Neuroscience, Scientific-Research Centre, I.M. Sechenov First Moscow State Medi cal University, Moscow; University headache clinic, MoscowRussian Federation

Кафедра генетики биологического факультета МГУ им. М.В. ЛомоносоваРоссияBioiogical faculty of Lomonosov Moscow State University, MoscowRussian Federation

2013

23122015

12437

2015

Азимова Ю.Э., Климов Е.А., Скоробогатых К.В., Сергеев А.В., Кокаева З.Г., Табеева Г.Р.

Azimova J.E., Klimov Е.А., Skorobogatykh K.V., Sergeev А.V., Kokaeva Z.G., Tabeeva G.R.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.medgen-journal.ru/jour/article/view/44

Семейная гемиплегическая мигрень — единственный тип мигрени с хорошо изученным молекулярно-генетическим механизмом. Это достаточно редкое неврологическое заболевание человека, описанное всего в 200 семьях во всем мире и единично встречающееся в спорадических формах. Однако понимание молекулярных механизмов гемиплегической мигрени расширяют наши представления об этиологии классической мигрени. В настоящем обзоре представлена имеющаяся на сегодняшний день информация о генетический основе гемиплегической мигрени, её клинической картине, дан краткий обзор подходов к лечению.

Familial hemiplegic migraine is only one type of migraine with well-studied molecular genetic mechanism. This is a rare neurological disease of humans that is described only in 200 families worldwide and in sporadic forms. However, understanding of the molecular mechanisms of hemiplegic migraine expands our understanding of the etiology of classical migraine. In this review available to date information about the genetic basis of hemiplegic migraine, its clinical presentations and a brief overview of approaches to treatment are presented.

гемиплегическая мигреньсемейная гемиплегическая мигреньмутации

hemiplegic migrainefamillal hemiplegic migrainemutations

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The authors declare that there are no conflicts of interest present.