medgenМедицинская генетикаMedical Genetics2073-7998Publishing House «Genius Media» LLC10.1234/XXXX-XXXX-2013-2-3-12medgen-37Research ArticleНАУЧНЫЕ ОБЗОРЫREVIEWГЕНЕТИЧЕСКИЕ НАРУШЕНИЯ ВЕСТИБУЛЯРНОЙ СИСТЕМЫGENETIC DISORDERS OF VESTIBULAR SYSTEMМглинецВ. А.MglinetsV. A.mglinetz@med-gen.ruФедеральное государственное бюджетное учреждение «Медико-генетический научный центр» Российской академии медицинских наукРоссияResearch Centre for Medical GeneticsRussian Federation201323122015122312Copyright © Мглинец В.А., 20152015Мглинец В.А.Mglinets V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.medgen-journal.ru/jour/article/view/37

Рассмотрены некоторые генетические нарушения вестибулярного аппарата (ВА) у модельных животных. Эти нарушения, в основном, затрагивают формирование или всего ВА, или полукружных каналов, сферического, эллиптического или эндо-лимфатического мешочка. Нарушения могут касаться и нейрального или сенсорного компонентов ВА. Рассмотрены также нарушения образования отоконий и эндолимфы ВА. Приведены некоторые нарушения ВА у человека.

 

Some genetic disorders of vestibular apparatus in animal models are considered in this review. These disorders mainly affect the formation or the entire vestibu I ar system, or the semicircul ar chanals, as well as spheri cal sac, el l iptical sac or endolymphatic sac. Disorders may also involve neural or sensory components of the vestibular apparatus. Disorders of formation and functioning of otoconia and vestibu I ar endolymph are also considered. Some vestibul ar disorders in humans are discussed.

 

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The authors declare that there are no conflicts of interest present.