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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medgen</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская генетика</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Genetics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7998</issn><publisher><publisher-name>Publishing House «Genius Media» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25557/2073-7998.2020.11.83-84</article-id><article-id custom-type="elpub" pub-id-type="custom">medgen-1808</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF REPORT</subject></subj-group></article-categories><title-group><article-title>Генетические аспекты идиопатической формы привычного невынашивания беременности</article-title><trans-title-group xml:lang="en"><trans-title>Genetic aspects of the idiopathic form of habitual miscarriage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Святова</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Svyatova</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">gsvyatova1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березина</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezina</surname><given-names>G. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муртазалиева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Murtazaliyeva</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Акционерное общество «Научный центр акушерства, гинекологии и перинатологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Scientific Center of Obstetrics, Gynecology and Perinatology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>02</day><month>02</month><year>2021</year></pub-date><volume>19</volume><issue>11</issue><fpage>83</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Святова Г.С., Березина Г.М., Муртазалиева А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Святова Г.С., Березина Г.М., Муртазалиева А.В.</copyright-holder><copyright-holder xml:lang="en">Svyatova G.S., Berezina G.M., Murtazaliyeva A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medgen-journal.ru/jour/article/view/1808">https://www.medgen-journal.ru/jour/article/view/1808</self-uri><abstract><p>Проведенное исследование позволило определить этиологическую обусловленность идиопатических форм привычного невынашивания беременности нарушениями иммунного взаимодействия материнских клеток с синцитиотрофобластом, а также носительством неблагоприятных аллелей риска главного комплекса гистосовместимости HLA 2 класса.</p></abstract><trans-abstract xml:lang="en"><p>The first time made conducted study to determine the possible etiological condition of idiopathic forms of recurrent miscarriage by impaired immune interaction of maternal cells with syncytiotrophoblast, as well as by carriage of adverse risk alleles of the main HLA histocompatibility complex class 2.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиморфизм генов</kwd><kwd>генотипы</kwd><kwd>идиопатическая форма</kwd><kwd>невынашивание беременности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gene polymorphism</kwd><kwd>genotypes</kwd><kwd>idiopathic form</kwd><kwd>habitual miscarriage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Manning A. 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