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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medgen</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская генетика</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Genetics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7998</issn><publisher><publisher-name>Publishing House «Genius Media» LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25557/2073-7998.2020.10.71-72</article-id><article-id custom-type="elpub" pub-id-type="custom">medgen-1742</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF REPORT</subject></subj-group></article-categories><title-group><article-title>Этические проблемы митохондриального замещения</article-title><trans-title-group xml:lang="en"><trans-title>Ethical problems of mitochondrial replacement</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Введенская</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vvedenskaya</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">vvedenskaya.elena@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт научной информации по общественным наукам (ИНИОН) РАН; ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of scientific information on social Sciences (INION) of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>14</day><month>12</month><year>2020</year></pub-date><volume>19</volume><issue>10</issue><fpage>71</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Введенская Е.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Введенская Е.В.</copyright-holder><copyright-holder xml:lang="en">Vvedenskaya E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medgen-journal.ru/jour/article/view/1742">https://www.medgen-journal.ru/jour/article/view/1742</self-uri><abstract><p>Применение любой новой вспомогательной репродуктивной технологии, связанной с манипуляциями человеческими половыми клетками и эмбрионами неизбежно будет спорным с этической точки зрения. Такой технологией является митохондриальное замещение, которое позволяет родить здорового ребенка женщине, страдающей митохондриальным заболеванием.</p></abstract><trans-abstract xml:lang="en"><p>The use of any new assisted reproductive technology related to the manipulation of human sex cells and embryos will inevitably be controversial from an ethical point of view. This technology is mitochondrial replacement, which allows a woman suffering from mitochondrial dysfunction to give birth to a healthy child.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>митохондриальное замещение</kwd><kwd>митохондриальные заболевания</kwd><kwd>этика</kwd><kwd>«феномен наклонной плоскости»</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mitochondrial replacement</kwd><kwd>mitochondrial diseases</kwd><kwd>ethics</kwd><kwd>inclined plane phenomenon</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pfeffer G., Majamaa K., Turnbull D.M., Thorburn D., Chinnery P.F. Treatment for mitochondrial disorders. Cochrane Database Syst. Rev. 2012; 18:CD004426.</mixed-citation><mixed-citation xml:lang="en">Pfeffer G., Majamaa K., Turnbull D.M., Thorburn D., Chinnery P.F. Treatment for mitochondrial disorders. Cochrane Database Syst. 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