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<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medgen</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинская генетика</journal-title><trans-title-group xml:lang="en"><trans-title>Medical Genetics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2073-7998</issn><publisher><publisher-name>Publishing House «Genius Media» LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medgen-1684</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF REPORT</subject></subj-group></article-categories><title-group><article-title>Ассоциации полиморфизма rs1801197 гена рецептора кальцитонина CALCR с постменопаузальным остеопорозом</article-title><trans-title-group xml:lang="en"><trans-title>Associations of rs1801197 polymorphism of the calcitonin receptor gene CALCR with postmenopausal osteoporosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Резниченко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Reznichenko</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Адунц</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Adunts</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">anna.adync@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Медицинская академия имени С.И. Георгиевского ФГАОУ ВО «Крымский федеральный университет имени В.И. Вернадского»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Academy named after S.I. Georgievsky of Vernadsky CFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Донецкое клиническое территориальное медицинское объединение</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Donetsk Clinical Territorial Medical Association</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>26</day><month>11</month><year>2020</year></pub-date><volume>19</volume><issue>8</issue><fpage>63</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Резниченко Н.А., Адунц А.Г., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Резниченко Н.А., Адунц А.Г.</copyright-holder><copyright-holder xml:lang="en">Reznichenko N.A., Adunts A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.medgen-journal.ru/jour/article/view/1684">https://www.medgen-journal.ru/jour/article/view/1684</self-uri><abstract><p>Обследовано 116 женщин в постменопаузе. Установлено неравномерное распределение генотипов полиморфизма rs1801197 гена CALCR в группах здоровых женщин, пациентов с остеопорозом и остеопенией (р=0,036). Среди женщин с остеопорозом и остеопенией по сравнению со здоровыми лицами значительно чаще регистрируется аллель С (p&lt;0,001).</p></abstract><trans-abstract xml:lang="en"><p>We examined 116 postmenopausal women. An uneven distribution of the rs1801197 polymorphism genotypes of the CALCR gene was found in the groups of healthy women, patients with osteoporosis and osteopenia (p = 0.036). Among women with osteoporosis and osteopenia, compared with healthy individuals, the C allele is significantly more often recorded (p &lt;0.001).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>постменопауза</kwd><kwd>остеопороз</kwd><kwd>полиморфизм rs1801197</kwd><kwd>ген CALCR</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoporosis</kwd><kwd>rs1801197 polymorphism</kwd><kwd>CALCR gene</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
